Carbamazepine

Selected References:

  • Antonucci R, et al. 2018. Maternal carbamazepine therapy and unusual adverse effects in a breastfed infant. Breastfeed Med 13(2):155-157.
  • Baker GA, et al. 2015. IQ at 6 years after in utero exposure to antiepileptic drugs: a controlled cohort study. Neurology 84(4):382-90.
  • Bech BH, et al. 2014. Use of antiepileptic drugs during pregnancy and risk of spontaneous abortion and stillbirth: population based cohort study. BMJ 349:g5159
  • Blotiere PO. et al. 2020. Risk of early neurodevelopmental outcomes associated with prenatal exposure to the antiepileptic drugs most commonly used during pregnancy: a French nationwide population-based cohort study. BMJ Open. 7;10(6):e034829.
  • Campbell E, et al. 2014. Malformation risks of antiepileptic drug monotherapies in pregnancy: updated results from the UK and Ireland Epilepsy and Pregnancy Registers. J Neurol Neurosurg Psychiatry Sep;85(9):1029-34.
  • Canger R, et al. 1999. Malformations in offspring of women with epilepsy: a prospective study. Epilepsia 40(9):1231-1236.
  • Davanzo R, et al. 2013. Italian Journal of Pediatrics 39:50-61.
  • Deshmukh U, et al. 2016. Behavioral outcomes in children exposed prenatally to lamotrigine, valproate, or carbamazepine. Neurotoxicol Teratol 54:5-14.
  • Fried S, et al. 2004. Malformation rates in children of women with untreated epilepsy: a meta-analysis.  Drug Saf 27(3):197-202.
  • Gaily E, et al. 2004. Normal intelligence in children with prenatal exposure to carbamazepine. Neurology 62:28-32.
  • Gladstone DJ, et al. 1992. Course of pregnancy and fetal outcome following maternal exposure to carbamazepine and phenytoin: a prospective study. Reprod Toxicol 6:257-61.
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  • Hernandez-Diaz S, et al. 2000. Folic acid antagonists during pregnancy and the risk of birth defects. N Engl J Med 343(22):1608-1614.
  • Huber-Mollema Y. et al. 2020. Neurocognition after prenatal levetiracetam, lamotrigine, carbamazepine, or valproate exposure. J Neurol. 267(6):1724-1736.
  • Husebye E. et al. 2020. Language impairment in children aged 5 and 8 years after antiepileptic drug exposure in tuero – the Norwegian Mother and Child Cohort Study. European Journal of Neurology 27.3:667-675.
  • Jones KL, et al. 1989. Patterns of malformations in the children treated with carbamazepine during pregnancy. N Engl J Med 320(25):1661-66.
  • Kallen AJB. 1994. Maternal carbamazepine and infant spina bifida. Reprod Toxicol 8(3):203-205.
  • Meador KJ, et al. 2009. Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs. N Engl J Med 360(16):1597-1605.
  • Margulis A. et al. 2019. Relation of in-utero exposure to antiepileptic drugs to pregnancy during and size at birth. PLoS One. Aug; 5;14(8):e0214180.
  • Meador KJ, et al. 2014. Breastfeeding in children of women taking antiepileptic drugs cognitive outcomes at age 6 years. JAMA Pediatr Aug;168(8):729-36.
  • Morrell M. 1996. The new antiepileptic drugs and women: efficacy, reproductive health, pregnancy and fetal outcome. Epilepsia 37(Suppl. 6):S34-S44.
  • Nulman I, et al. 1997. Findings in children exposed in utero to phenytoin and carbamazepine monotherapy: independent effects of epilepsy and medications. Am J Med Genet 68:18-24.
  • O’Brien MD and Gilmour-White SK. 2005. Management of epilepsy in women treated with carbamazepine during pregnancy. Postgrad Med J 81(955):278-285.
  • Ornoy A and Cohen E.   Outcome of children born to epileptic mothers treated with carbamazepine during pregnancy. Arc Dis Child 75:517-20
  • Patel N, et al. 2018. Mood-stabilizing anticonvulsants, spina bifida, and folate supplementation: commentary. J Clin Psychopharmacol 38(1):7-10.
  • Rosa FW. 1991. Spina bifida in infants of women treated with carbamazepine during pregnancy. N Engl J Med 324(10)674-677.
  • Samren EB, et al. 1999. Antiepileptic drug regimens and major congenital abnormalities in the offspring. Ann Neurol 46(5):739-746.
  • Scolnik D, et al. 1994. Neurodevelopment if children exposed in utero to phenytoin and carbamazepine monotherapy. JAMA 271(10):767-770.
  • Tomson T and Barrino D. Teratogenic effects of antiepileptic drugs. Seizure 17(2):166-171.
  • Tomson T and Klein P. 2015. Fine-tuning risk assessment with antiepileptic drug use in pregnancy. Neurology. 84(4):339-40.
  • Tomson T, et al. 2015. Antiepileptic drugs and intrauterine death: A prospective observational study from EURAP. Neurology Aug 18;85(7):580-8.
  • Tomson T, et al. 2018. Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry. Lancet Neurol 17(6):530-8.
  • Vajda F. 2014. Epilepsy: Effects of exposure to antiepileptic drugs during development. Nat Rev Neurol.10:11-2.
  • Vajda F, et al. 2018. Anti-epileptic drug exposure and risk of foetal death in utero. Acta Neurol Scand Jan;137(1):20-23.
  • Wallace H, et al. 1998. Age-specific incidence and prevalence rates of treated epilepsy in an unselected population of 2,052,922 and age-specific fertility rates of women with epilepsy. Lancet 352:1970-73.
  • Weston J, et al. 2016. Monotherapy treatment of epilepsy in pregnancy: congenital malformation outcomes in the child. Cochrane Database Syst Rev.11:Cd010224.
  • Wide K, et al. 2000. Psychomotor development and minor anomalies in children exposed to antiepileptic drugs in utero: a prospective population-based study. Dev Med Child Neurol 42:87-92.
  • Wiggs K. et al. 2020. Anti-seizure medication use during pregnancy and risk of ASD and ADHD in children. Neurology. [Published online ahead of print October 27, 2020] Aoki FY, et al. 2013. The use of antiviral drugs for influenza: A foundation document for practitioners. Can J Infect Dis Med Microbiol. 24(Suppl C) :1-15.

Carbamazepine

Selected References:

  • Aporta RR, et al. 1998. Alglucerase enzyme replacement therapy used safely and effectively throughout the whole pregnancy of a Gaucher disease patient. Haematologica. 83:852-3.
  • Amory, JK, et al. 2007. Miglustat has no apparent effect on spermatogenesis in normal men. Human Reproduction, 22(3), 702–707.
  • Dornelles AD, et al. 2014. Breastfeeding in Gaucher disease: is enzyme replacement therapy safe? Clin Ther.36:990-1.
  • Elstein Y, et al. 2004. Pregnancies in Gaucher disease: a 5-year study. Am J Obstet Gynecol. 190(2):435-41.
  • Elstein D et al. 2014. Outcome of pregnancies in women receiving velaglucerase alfa for Gaucher disease. J Obstet Gynaecol Res.40(4):968-975.
  • Gary, Sam E. et al. Recent Advances in the Diagnosis and Management of Gaucher Disease. Expert Review of Endocrinology & Metabolism. 13(2): 107–18
  • Giannubilo SR, et al. 2015. Replacement therapy for Gaucher disease during pregnancy: A case report. J Reprod Infertil 16(1): 53-57.
  • Granovsky-Grisaru, S et al. 2011. The management of pregnancy in Gaucher disease. Eur I Obstet Gynecol Reprod Biol. 156: (1) 3-8.
  • Komninaka V, et al. 2020. Outcomes of pregnancies in patients with Gaucher Disease: The experience of a center of excellence on rare metabolic Disease-Gaucher Disease, in Greece. Eur J Obstet Gynecol Reprod Biol. 254:181-187.
  • Korkmazer E, et al. 2015. Pregnancy and lactation in a patient with Gaucher disease receiving enzyme replacement therapy: Case report. Turkey J Clin Obstet Gynecol. 25:224-6.
  • Lau H, et al. 2018. Reported outcomes of 453 pregnancies in patients with Gaucher disease: An analysis from the Gaucher outcome survey. Blood Cells Mol Dis. 68:226-231.
  • Mamopoulos A M et al. 2009. Gaucher disease and pregnancy. J Obstet Gynaecol. 29: 240-242.
  • Murphy E. 2015. Pregnancy in women with inherited metabolic disease. Obstet Med. 8(2): 61-67.
  • Paskulin L, et al. Breastfeeding in patients with Gaucher disease: Is taliglucerase alfa safe? Molecular Genetics and Metabolism Reports, 18, 30–31.
  • Rosenbaum H. 2015. Management of women with Gaucher disease in the reproductive age. Thromb Res. 135 Suppl 1:S49-51.
  • Roy, A., et al. 2006. Shaping the sperm head: an ER enzyme leaves its mark. Journal of Clinical Investigation, 116(11), 2860–2863.
  • Sekijima Y, et al. 2010. Successful pregnancy and lactation outcome in a patient with Gaucher disease receiving enzyme replacement therapy, and the subsequent distribution and excretion of Imiglucerase in human breast milk. Clin Ther. 32(12): 2048-2052.
  • Sherer Y, et al. 2002. Successful suc outcome in a patient with Gaucher’s disease and antiphospholipid syndrome. Ann Hematol. 81:161-3.
  • Stirnemann J, et al. A Review of Gaucher Disease Pathophysiology, Clinical Presentation and Treatments. International Journal of Molecular Sciences, 18(2), 441.
  • Weinreb, N. J. 2008. Imiglucerase and its use for the treatment of Gaucher’s disease. Expert Opinion on Pharmacotherapy, 9(11), 1987–2000.
  • Zimran A, et al. 2009. The female Gaucher patient: the impact of enzyme replacement therapy around key reproductive events. Blood Cells Mol Dis. 43:264-288.

Carbamazepine

Selected References:

  • Berle JO, et al. 2004. Breastfeeding during maternal antidepressant treatment with serotonin reuptake inhibitors: infant exposure, clinical symptoms, and cytochrome P450 genotypes. J Clin Psychiatry 65:1228-34. PMID: 15367050
  • Brunel P, et al. 1994. [Follow-up of 151 pregnant women exposed to antidepressant treatment (MAOI excluded) during organogenesis.] Therapie 49:117-122.
  • Eggermont E. 1973. Withdrawal symptoms in neonate associated with maternal imipramine therapy. Lancet 2:680.
  • Misri S & Sivertz K. 1991. Tricyclic drugs in pregnancy and lactation: a preliminary report. Int J Psychiatry Med 21(2):157-71.
  • Mitchell JE and Popkin MK: Antidepressant drug therapy and sexual dysfunction in men: a review. J Clin Psychopharm 3:76-79, 1983.
  • Nulman I, et al. 1997. Neurodevelopment of children exposed in utero to antidepressant drugs. N Engl J Med 336:258-62.
  • Overo KF, et al. 1997. Interaction of perphenazine with the kinetics of nortriptyline. Acta Pharmacol Toxicol; 40:97-105.
  • Shearer WT, et al. 1972. Urinary retention in a neonate secondary to maternal ingestion of nortriptyline. J Pediatr 81:570-2.
  • Schoretsanitis S, et al. 2020. The impact of pregnancy on the pharmacokinetics of antidepressants: a systematic critical review and meta-analysis. Expert Opin Drug Metab Toxicol; 16(5):431-440.
  • US Preventive Services Task Force, Curry SJ, et al. 2019. Interventions to Prevent Perinatal Depression: US Preventive Services Task Force Recommendation Statement. JAMA 321(6):580-587.
  • Webster PA. 1973. Withdrawal symptoms in neonates associated with maternal antidepressant therapy. Lancet 2(7824):318-9.
  • Weissman AM, et al. Pooled analysis of antidepressant levels in lactating mothers, breast milk, and nursing infants. Am J Psychiatry 161:1066-78. PMID: 15169695
  • Wisner KL, et al. 2002. Postpartum depression. N Engl J Med. 347:194-9. PMID: 12124409.

Carbamazepine

Selected References

  • Alfaraj SH, et al. 2019. Middle east respiratory syndrome coronavirus (MERS-CoV) infection during pregnancy: report of two cases & review of the literature. J Microbiol Immunol Infect 52(3):501-503.
  • Alserehi H, et al. 2016. Impact of middle east respiratory syndrome coronavirus (MERS-CoV) on pregnancy and perinatal outcome. BMC Infect Dis 16:105.
  • Assiri A, et al. 2016. Middle east respiratory syndrome coronavirus infection during pregnancy: a report of 5 cases from Saudi Arabia. Clin Infect Dis 1;63(7):951-3.
  • Centers for Disease Control and Prevention. 2020. 2019 Novel Coronavirus: Interim Guidance for Healthcare Professionals. Available at URL: https://www.cdc.gov/coronavirus/2019-ncov/hcp/clinical-criteria.html. [Accessed 1/2020].
  • Centers for Disease Control and Prevention. 2020. Coronavirus: Prevention and Treatment. Available at URL: https://www.cdc.gov/coronavirus/about/prevention.html. [Accessed 1/2020].
  • Centers for Disease Control and Prevention. 2019. Coronavirus: Symptoms and Diagnosis. Available at URL: https://www.cdc.gov/coronavirus/about/symptoms.html. [Accessed 1/2020].
  • Centers for Disease Control and Prevention. 2019. Coronavirus: Transmission. Available at URL: https://www.cdc.gov/coronavirus/about/transmission.html. [Accessed 1/2020].
  • Jeong SY, et al. 2017. MERS-CoV infection in a pregnant woman in Korea. J Korean Med Sci 32(10):1717-1720.
  • Malik A, et al. 2013. Middle east respiratory syndrome coronavirus during pregnancy, Abu Dhabi, United Arab Emirates, 2013. Emerg Infect Dis 22(3):515-7.
  • Payne DC, et al. 2014. Stillbirth during infection with middle east respiratory syndrome coronavirus. J Infect Dis 15;209(12):1870-2.
  • Shek CC, et al. 2003. Infants born to mothers with severe acute respiratory syndrome. Pediatrics 112(4):e254.
  • Wong SF, et al. 2004. Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome. Am J Obstet Gynecol 191(1):292-7.

Carbamazepine

Selected References

Carbamazepine
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