Rigorously Designed Research
MotherToBaby Pregnancy Studies partners with physicians and patients to monitor pregnancy exposure to select medications. Our strong cohort study design allows our team to tease apart risks that may be associated with underlying disease versus those associated with a medication exposure, resulting in evidence-based findings that you and pregnant your patients can use when making treatment decisions.
Referral Is Easy & Patients Self-Enroll
1- Refer: All you need to do is refer your patients to us. Women self-enroll, so after you make the referral nothing further is required from you.
2 – Observation: Our research is by observation only — we will not ask your patient to take or change any medications or change any part of her healthcare routine
3 – Participation: Women complete 1-3 phone interviews during pregnancy and at least 1 after pregnancy, and authorize the release of medical records for the pregnancy and for their baby.
Please consider referring your patients if they fall into either of these two groups:
- Patients who have taken any of the following medications during a current pregnancy:
- Apremilast (Otezla®)
- Benralizumab (Fasenra®)
- Certolizumab-pegol (Cimzia®)
- COVID-19 Vaccines
- Dupilumab (Dupixent®)
- Guselkumab (Tremfya®)
- Leflunomide (Arava®)
- Mepolizumab (Nucala®)
- Prucalopride (Motegrity®)
- Teriflunomide Aubagio®
- Tildrakizumab (Ilumya™)
- Tocilizumab (Actemra®)
- Tofacitinib (Xeljanz®)
- Sarilumab (Kevzara®)
2. Patients who have the following conditions and have not taken the above medications during pregnancy.
- Ankylosing Spondylitis
- Atopic Dermatitis
- Crohn’s Disease
- Functional Constipation
- Juvenile Idiopathic Arthritis
- Multiple Sclerosis
- Psoriatic Arthritis
- Rheumatoid Arthritis
- Ulcerative Colitis
Patient Education & Provider Resources
MotherToBaby is a service of the non-profit Organization of Teratology Information Specialists (OTIS). In addition to conducting pregnancy registry studies, we are dedicated to providing no-cost evidence-based information to mothers and health professionals about medications and other exposures during pregnancy and lactation. We can provide you with patient and provider resources including:
- Patient-friendly Fact Sheets
- Patient Brochures
- Teratogen Information Services
Refer Your Patient to Our Observational Studies
Find out more about our observational pregnancy research studies by contacting our team. Our staff is dedicated to supporting healthcare professionals. Please select if you would like to learn more about patient referrals or to learn more about our resources.
Advancing Medication Safety Information in Pregnancy
The Society for Maternal-Fetal Medicine is partnering with MotherToBaby Pregnancy Studies to encourage our member physicians to refer your pregnant patients to pregnancy exposure registries. With your help, these registries will yield much-needed safety information on medication use in pregnancy.
MotherToBaby Pregnancy Studies are conducted by the Organization of Teratology Information Specialists (OTIS) and coordinated by the University of California San Diego. MotherToBaby is listed as a resource for information about medications in pregnancy by the US Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC).