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Medications and More during pregnancy and breastfeeding

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Metoclopramide

Selected References

  • Allen RW. 2012. Metoclopramide–a safe anti-emetic? [letter] S Afr Med J; 77: 219, 1990.
  • Anderka M, et al. 2012. Medications used to treat nausea and vomiting of pregnancy and the risk of selected birth defects. Birth Defects Res (Part A); 94:22-30.
  • Andersen AN, Tabor A. 1982. Prl, TSH, GH and LH responses tometoclopramide and breastfeeding in normal and hyperprolactinaemic women. Acta Endocrinol (Copenh); 100:177-83.
  • Balikci A, Balibey H. 2012. [Postpartum depression due to use ofmetoclopramide: A case report]. Anatolian J Clin Invest; 6:258-60.
  • Bérard A, et al. 2019. New Evidence for Concern Over the Risk of Birth Defects from Medications for Nausea and Vomiting of Pregnancy. J Clin Epidemiol; 116: 39-48.
  • Berkovitch M, et al. 2002. Metoclopramide for nausea and vomiting of pregnancy: a prospective multicenter international study. Am J Perinatol; 19:311-6.
  • Çekmez Y, et al. 2016. Does metroclopramide exposure alter endometrial receptivity and decrease pregnancy rates? J Matern Fetal Neonatal Med 29(16): 2703-6
  • Dastgerdi E, et al. 2011. Effect ofmetoclopramide on increased milk production in mothers of preterm infants. Iran J Obstet Gynecol Infertil; 14:32-6.
  • Fife S, et al. 2011.Metoclopramide to augment lactation, does it work? A randomized trial. J Matern Fetal Neonatal Med; 24:1317-20.
  • Finnis WA, et al. 1976.Metoclopramide hydrochloride and galactorrhea. Can Med Assoc J; 115:845.
  • Ingram J, et al. 2012.Metoclopramide or domperidone for increasing maternal breast milk output: a randomised controlled trial. Arch Dis Child Fetal Neonatal Ed; 97:F241-5.
  • Kauppila A, et al. 1981.Metoclopramide increases prolactin release and milk secretion in puerperium without stimulating the secretion of thyrotropin and thyroid hormones. J Clin Endocrinol Metab; 52:436-9.
  • Kauppila A, et al. 1983.Metoclopramide and breast feeding: transfer into milk and the newborn. Eur J Clin Pharmacol; 25:819-23.
  • Kauppila A, et al. 1985.Metoclopramide and breast feeding: efficacy and anterior pituitary responses of the mother and the child. Eur J Obstet Gynecol Reprod Biol; 19:19-22.
  • Lewis PJ, et al. 1980. Controlled trial ofmetoclopramide in the initiation of breast feeding. Br J Clin Pharmacol; 9:217-9.
  • Matok I, et al. 2009. The Safety of Metoclopramide Use in the First Trimester of Pregnancy. N Engl J Med; 360:2528-2535.
  • Milo R, et al. 1989. Acute intermittent porphyria in pregnancy. Obstet Gynecol 73:450-2.
  • Nageotte MP, et al. 1996. Droperidol and diphenhydramine in the management of hyperemesis gravidarum. Am J Obstet Gynecol; 174:1801-1805.
  • Pasternak B, et al. 2013. Metoclopramide in pregnancy and risk of major congenital malformations and fetal death. JAMA. 310(15):1601-11.
  • Sakha R, Behbahan AG. 2008. Training for perfect breastfeeding ormetoclopramide: which one can promote lactation in nursing mothers? Breastfeed Med; 3:120-3.
  • Shenhav S, et al. 1997. Acute intermittent porphyria precipitated by hyperemesis and metoclopramide treatment in pregnancy. Acta Obstet Gynecol Scand;76:484-5.