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MotherToBaby

Medications and More during pregnancy and breastfeeding

Rheumatoid Arthritis

Selected References:

  • Aljary H et al. 2020. Pregnancy outcomes in women with rheumatoid arthritis: a retrospective population-based cohort study. The Journal of Maternal-Fetal & Neonatal Medicine, 33;4:618-624.Atladóttir HO, et al. 2009. Association of family history of autoimmune diseases and autism spectrum disorders. Pediatr, 124:687-694.
  • Bandoli G et al. 2020. Mediation of adverse pregnancy outcomes in autoimmune conditions by pregnancy complications. Arthritis Care Res, 72(2):256-264.
  • Bermas BL, Sammaritano LR. 2015. Fertility and pregnancy in rheumatoid arthritis and systemic lupus erythematosus. Fertil Res Pract. 2015 Aug 27;1:13.
  • Bourg M et al. 2020. Fertility and sexuality of women with inflammatory arthritis. European Journal of Obstetrics & Gynecology and Reproductive Biology, 251:199-205.
  • Brouwer J, et al. 2015. Brief report: Miscarriages in female rheumatoid arthritis patients: Associations with serologic findings, disease activity, and antirheumatic drug treatment. Arthritis Rheumatol, 67(7):1738-1743.
  • Brouwer J, et al. 2015. Fertility in women with rheumatoid arthritis: influence of disease activity and medication. Ann Rheum Dis, 74(10):1836-1841.
  • Brouwer J, et al.2917.Subfertility in Women With Rheumatoid Arthritis and the Outcome of Fertility Assessments. Arthritis Care Res (Hoboken). 2017 Aug;69(8):1142-1149.
  • Comi AM, et al. 1999. Familial clustering of autoimmune disorders and evaluation of medical risk factors in autism. J Child Neurol, 14:388-394
  • de Man YA, et al. 2014. Disease activity or remission of rheumatoid arthritis before, during and following pregnancy. Curr Opin Rheumatol, 26(3):329-333.
  • de Man YA, et al. 2008. Disease activity of rheumatoid arthritis during pregnancy: results from a nationwide prospective study. Arthritis Rheumatol, 59(9):1241-1248.
  • De Santis M, et al. 2005. Paternal and maternal exposure to leflunomide: pregnancy and neonatal outcome. Ann Rheum Dis, 64(7):1096-1097.
  • Dissanayke TD et al. 2020. Peripartum issues in the inflammatory arthritis patient: a survey of the RAPPORT registry. Nature Scientific Report, 10:3733.
  • Ekström K, et al. 2003. Risk of malignant lymphomas in patients with rheumatoid arthritis and in their first-degree relatives. Arthritis Rheum, 48:963-970.
  • Fischer-Betz R, et al. 2015. High risk of flares during pregnancy in women with rheumatoid arthritis who discontinue treatment with TNF Inhibitors at conception. Arthritis Rheumatol, 67(suppl 10).
  • Förger F, et al. 2012. Pregnancy mediated improvement of rheumatoid arthritis. Swiss Med Wkly, 142:w13644.
  • Förger F et al. 2019. Discontinuing TNF-inhibitors before gestational week 20 in well controlled rheumatoid arthritis and juvenile arthritis is not associated with a disease worsening in late pregnancy. Arthritis and Rheumatology, 71(6)901-907.
  • Ikram N, Eudy A, Clowse MEB. 2021. Breastfeeding in women with rheumatic diseases. Lupus Sci Med. Apr;8(1):e000491. Childbearing decisions and family size among women with rheumatoid arthritis. Arthritis Rheum, 55(2):217-223.
  • Keeling SO et al. 2020. A population-level analysis of the differing effects of rheumatoid arthritis and spondyloarthritis on peripartum outcomes. J Rheumatol, 47:197-203.
  • Krause ML, Makol A. 2016. Management of rheumatoid arthritis during pregnancy: challenges and solutions. Open Access Rheumatol, 8:23-36.
  • Littlejohn, Emily A. 2020. Pregnancy and rheumatoid arthritis. Best Practice & Research Clinical Obstetrics and Gynaecology.64: 52-58
  • Mahadevan U, et al. 2014. 960 Exposure to anti-TNFα therapy in the third trimester of pregnancy is not associated with increased adverse outcomes: Results from the PIANO Registry. Gastroenterol, 146(5), Suppl 1:S-170.
  • Mellemkjær L, et al. 2000. Cancer among children of parents with autoimmune diseases. Br J Cancer, 82:1353-1357.
  • Nathan NO et al. 2020. Rheumatoid arthritis and risk of spontaneous abortion: a Danish nationwide cohort study. Rheumatology, 59:1984-1991.
  • Østensen M, et al. 2015. State of the art: Reproduction and pregnancy in rheumatic diseases. Autoimmun Rev, 14(5):376-86.
  • Park JS et al. 2022. Risk of pregnancy complications and low birth weight offsprings in Korean women with rheumatic diseases: a nationwide population-based study. J Korean Med Sci; 37(2):e18
  • Rom AL, et al. 2016. Parental rheumatoid arthritis and long-term child morbidity: a nationwide cohort study. Ann Rheum Dis, 75:1831-1837
  • Spinillo A, et al. 2016. The impact of unrecognized autoimmune rheumatic diseases on the incidence of preeclampsia and fetal growth restriction: a longitudinal cohort study. BMC Pregnancy Childbirth, 16(1):313.
  • van den Brandt S, et al. 2017. Risk factors for flare and treatment of disease flares during pregnancy in rheumatoid arthritis and axial spondyloarthritis patients. Arthritis Res Ther, 19(1):64.
  • Viktil KK, et al. 2012. Outcomes after anti-rheumatic drug use before and during pregnancy: A cohort study among 50,000 pregnant women and expectant fathers. Scand J Rheumatol, 41(3):196-201.
  • Vinet, É and Bernatsky, S. 2017. Outcomes in children born to women with rheumatic diseases. Rheumatic Disease Clinics, 43(2):263-273.
  • Weber-Schoendorfer C, et al. 2014. No evidence for an increased risk of adverse pregnancy outcome after paternal low-dose methotrexate: an observational cohort study. Rheumatology (Oxford), 53(4):757-763.
  • Weber-Schoendorfer C, et al. 2015. Pregnancy outcome after TNF-α inhibitor therapy during the first trimester: a prospective multicentre cohort study. Br J Clin Pharmacol, 80(4):727-739.
  • Williams M and Chakravarty EF, 2014. Rheumatoid arthritis and pregnancy: impediments to optimal management of both biologic use before, during and after pregnancy. Curr Opin Rheumatol, 26(3):341-346.
  • Wojcik S, et al. 2015. Risk of autism spectrum disorders in children born to mothers with rheumatoid arthritis: a systematic literature review. J Rheumatol, 42:1263-1351.

MotherToBaby cuenta con el apoyo de la Administración de Recursos y Servicios de Salud (HRSA) del Departamento de Salud y Servicios Humanos de los Estados Unidos (HHS) como parte de una adjudicación por un total de $6,000,000 con cero porcentaje financiado con fuentes no gubernamentales. Los contenidos son los del autor/es y no representan necesariamente los puntos de vista oficiales de, ni un respaldo, por HRSA, HHS o el Gobierno de los Estados Unidos.