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Medications and More during pregnancy and breastfeeding

Sumatriptan

Selected References:

  • Amundsen S, et al. 2015. Pharmacological treatment of migraine during pregnancy and breastfeeding; Nat. Reviews Neurol. 11(4): 209-215. 
  • Bandoli G, et al. 2020. Migraines During Pregnancy and the Risk of Maternal Stroke. JAMA Neurol. 77(9):1177-79.  
  • Bánhidy F, et al. 2006. Maternal severe migraine and risk of congenital limb deficiencies. Birth Defects Res a Clin Mol Teratol. 76(8):592-601. 
  • Conijn M, et al. 2024. Breastfeeding-related adverse drug reactions of triptans: A descriptive analysis using four pharmacovigilance databases. Breastfeed Med. 19:645-51. 
  • Cunnington M, et al. 2009. The safety of sumatriptan and naratriptan in pregnancy: what have we learned? Headache. 49(10):1414-22. 
  • David PS, et al. 2014. Migraine in pregnancy and lactation. Curr Neurol Neurosci Rep. 14(4):439. 
  • Duong S, et al. 2010. Safety of triptans for migraine headaches during pregnancy and breastfeeding. Can Fam Physician. 56(6):537-9. 
  • Ephross AS, et al. 2014. Final results from the 16-year sumatriptan, naratriptan, and treximet pregnancy registry. Headache. 54(3):1158-1172. 
  • Harris GE, et al. 2018.  Prenatal triptan exposure and neurodevelopmental outcomes in 5-year-old children: Follow-up from the Norwegian Mother and Child Cohort Study. Paediatr Perinat Epidemiol. 32(3):247-255.  
  • Jarvis S, et al. 2018. Managing migraine in pregnancy. BMJ 360:k80. 
  • Källén B, et al. 2011. Delivery outcome after maternal use of drugs for migraine: a register study in Sweden. Drug Saf. 34(8):691-703. 
  • MacGregor AE, et al. 2014. Migraine in pregnancy and lactation. Neurol Sci. 35(Suppl 1): S61-S64. 
  • Marchenko A, et al. 2015. Pregnancy outcome following prenatal exposure to triptan medications: a meta-analysis. Headache. 55(10):1478.  
  • Miller C & Vollbracht S. 2021. Neurology of Preeclampsia and Related Disorders: An Update in Neuro-obstetrics. Curr Pain Headache Rep. 25(6):40.  
  • Negro A, et al. 2017. Headache and pregnancy: a systematic review. The Journal of Headache and Pain 18(1):106. 
  • Nezvalová-Henriksen K, et al. 2010. Triptan exposure during pregnancy and the risk of major congenital malformations and adverse pregnancy outcomes: results from the Norwegian Mother and Child Cohort Study. Headache. 50(4):563-75. 
  • Nezvalová-Henriksen K, et al. 2013. Triptan safety during pregnancy: a Norwegian population registry study. Eur J Epidemiol. 28(9):759-69. 
  • Olesen C, et al. 2000. Pregnancy outcome following prescription for sumatriptan. Headache. 40(1):20-4. 
  • Spielmann K, et al. 2018. Pregnancy outcome after anti-migraine triptan use: a prospective observational cohort. Cephalagia. 38(6):1081-1092. 
  • Wabnitz A, Bushnell C. 2015. Migraine, cardiovascular disease, and stroke during pregnancy: systematic review of the literature. Cephalalgia. 35(2):132-9. 
  • Wojnar-Horton RE, et al. 1996. Distribution and excretion of sumatriptan in human milk. Br J Clin Pharmacol. 41(3):217-21. 
  • Wood ME, et al. 2016. Prenatal Triptan Exposure and Internalising and Externalising Behaviour Problems in 3-Year-Old Children: Results from the Norwegian Mother and Child Cohort Study. Paediatr Perinat Epidemiol.  30(2):190-200. 

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