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Chlordiazepoxide (Librium®)

February 1, 2021

Selected References:

  • Athinarayanan P, et al. 1976. Chlordizaepoxide withdrawal in the neonate. Am J Obstet Gynecol 124:212-3.
  • Crombie DL, et al. 1975. Fetal effects of tranquilizers in pregnancy. New Eng J Med 293:198-9.
  • Czeizel A. 1988. Lack of evidence of teratogenicity of benzodiazepine drugs in Hungary. Reprod Toxicol 1:183-188.
  • Czeizel AE, Mosonyi A. 1997. Monitoring of early human fetal development in women exposed to large doses of chemicals. Environ Mol Mutagen 30:240-244.
  • Czeizel AE, et al. 1997. Teratologic evaluation of 178 infants born to mothers who attempted suicide by drugs during pregnancy. Obstet Gynecol 90:195-201.
  • Gidai J, et al. 2008. A study of the teratogenic and fetotoxic effects of large doses of chlordiazepoxide used for self-poisoning by 35 pregnant women. Toxicol Ind Health; 24(1-2):41-51.
  • Hartz SC, et al: Antenatal exposure to meprobamate and chlordiazepoxide in relation to malformations, mental development and childhood mortality. New Eng J Med 292:726-8, 1975.
  • Hughes JM. 1964. Failure to ejaculate with chlordiazepoxide. Am J Psychiatry 121:610-1.
  • Martino V. 1987. Mas M. Davidson JM. Chlordiazepoxide facilitates erections and inhibits seminal emission in rats. Psychopharmacology; 91:85-9.
  • Milkovich L, Van den Berg BJ. 1974. Effects of prenatal meprobamate and chlordiazepoxide hydrochloride on human embryonic and fetal development. New Eng J Med 291:1268-1271.
  • Stirrat GM, et al. 1974. Transplacental passage of chlordiazepoxide. Br Med J 2:729.

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