MotherToBaby

Medications and More during pregnancy and breastfeeding

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Clindamycin

Selected References:

  • Lamont RF. Et al. 2003. The efficacy of vaginal clindamycin for the treatment of abnormal genital tract flora in pregnancy. Infect Dis Obstet Gynecol 11(4):181-189.
  • Mackeen AD, et al. 2015. Antibiotic regimens for postpartum endometritis. Cochrane Database Syst Rev.2; 2:CD001067.
  • Mann CF. 1980. Clindamycin and breast-feeding. Pediatrics 66:1030-1.
  • McCormack WM, et al. 1987. Effect on birth weight of erythromycin treatment of pregnant women. Obstet Gynecol 69:202-207.
  • McGready R, et al. 2001. Randomized comparison of quinine-clindamycin versus artesunate in treatment of falciparum malaria in pregnancy. Trans R Soc Trop Med Hyg 95:651-656.
  • Mitrano JA, et al. 2009. Excretion of antimicrobials used to treat methicillin-resistant Staphylococcus aureus infections during lactation: safety in breastfeeding infants. Pharmacotherapy 29(9):1103-9.
  • Muanda F, et al. 2017. Use of antibiotics during pregnancy and the risk of major congenital malformations: a population based cohort study. Br J Clin Pharmacol 83:2557-2571.
  • Nahum GG, et al. 2006. Antibiotic use in pregnancy and lactation: what is and is not known about teratogenic and toxic risks. Obstet Gynecol 107(5):1120-38.
  • Onwuchuruba CN, et al. 2014. Transplacental passage of vancomycin from mother to neonate. Am J Obstet Gynecol 210(4):352.e1-4.
  • Ou MC, et al. 2001. Antibiotic treatment for threatened abortion during the early first trimester in women with previous spontaneous abortion. Acta Obstet Gynecol Scand 80(8):753-6.
  • Reboucas KF, et al. 2019. Treatment of bacterial vaginosis before 28 weeks of pregnancy to reduce the incidence of preterm labor. Int J Gynecol Obstet 146(3):271-6.
  • Smith JA, et al. 1975. Clindamycin in human breast milk. Can Med Assoc J 112:806
  • Steen B, Rane A. 1982. Clindamycin passage into human milk. Br J Clin Pharmacol 13:661-4.
  • Subtil D, et al. 2018. Early clindamycin for bacterial vaginosis in pregnancy (PREMEVA): a multicentre, double-blind, randomised controlled trial. Lancet 392(10160):2171-2179.
  • Ugwumadu A, et al. 2003. Effect of early oral clindamycin on late miscarriage and preterm delivery in asymptomatic women with abnormal vaginal flora and bacterial vaginosis: a randomised controlled trial. Lancet 361:983-88.
  • Weinstein AJ et al. 1976. Placental transfer of clindamycin and gentamicin in term pregnancy. Am J Obstet Gynecol 124:688-91.