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Fentanyl

August 1, 2021

Selected References:

  • Broussard CS, et al. 2011. National Birth Defects Prevention Study: Maternal treatment with opioid analgesics and risk for birth defects. Am J Obstet Gynecol. 204(4):314.e1–11.
  • Cohen RS 2009. Fentanyl transdermal analgesia during pregnancy and lactation. J Hum Lact, 25(3):359-361.
  • Fishman B, et al. 2019. Pregnancy outcome following opioid exposure: A cohort study. PLoS One 14(7): e0219061.
  • Fleet JA, et al. 2020. Fentanyl concentration in maternal and umbilical cord plasma following intranasal or subcutaneous administration in labour. Int J Obstet Anesth. 42:34-38.
  • Larson JJ, et al. 2019. Cognitive and behavioral impact on children exposed to opioids during pregnancy. Pediatrics 144(2): e20190514.
  • Lind JN, et al. 2017. Maternal use of opioids during pregnancy and congenital malformations: A systemic review. Pediatrics 139(6):e20164131.
  • Mahomed K, et al. 2019. Does fentanyl epidural analgesia affect breastfeeding: A prospective cohort study. Aust N Z J Obstet Gynaecol. 59(6):819-824.
  • Moore A, et al. 2016. Maternal Epidural Fentanyl Administered for Labor Analgesia Is Found in Neonatal Urine 24 Hours After Birth. Breastfeed Med. 11(1):40-1.
  • Nitsun M, et al. 2006. Pharmacokinetics of midazolam, propofol, and fentanyl transfer to human breast milk. Clin Pharmacol Ther, 79(6):549-557.
  • Regan J, et al. 2000. Neonatal abstinence syndrome due to prolonged administration of fentanyl in pregnancy. Br J Obstet Gynecol, 107:570-572.
  • Väänänen A, et al 2019. Spinal and epidural sufentanil and fentanyl in early labour. Acta Anaesthesiol Scand ;63(10):1413-1418.
  • Yazdy MM, et al. 2013. Periconceptional use of opioids and the risk of neural tube defects. Obstetrics and Gynecology, 122(4):838–844.

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