• Skip to primary navigation
  • Skip to main content
  • Skip to footer
MotherToBaby

MotherToBaby

Medications and More during pregnancy and breastfeeding

Search

Hide Search
Shopping Cart
Show SearchSearch
866.626.6847
  • About
    • Our Work
    • Our Team
    • Our Partners
  • Exposures
    • Pregnancy and Breastfeeding Exposures
    • Fact Sheets
    • Baby Blogs
    • Podcasts
    • LactRx App
  • Studies
    • Ongoing Studies
    • What’s Involved?
    • Join Now
    • Health Providers
    • Pharma Industry
    • Publications
  • Health Professionals
    • Patient Education and Provider Resources
    • Refer a Patient
    • Request Materials
    • Meetings
    • FAQs
    • OTIS Membership
  • Media
    • Media Requests
    • Press Releases
    • eNews Sign Up
  • In Your Area
  • OTIS
    • About OTIS
    • OTIS Membership
    • Annual Meeting
    • Member Log-In
    • Donate
  • Contact
  • Show SearchSearch

Losartan (Cozaar®)

June 1, 2021

Selected References:

  • Alwan S, et al. 2005. Angiotensin II receptor antagonist treatment during pregnancy. Birth Defects Res A Clin Mol Teratol. 73:123-130.
  • Bass JK, Faix RG. 2006. Gestational Therapy with an Angiotensin II Receptor Antagonist and Transient Renal Failure in a Premature Infant. Am J Perinatol. 23:313-318.
  • Daikha-Dahmane F, et al. 2006. Foetal kidney maldevelopment in maternal use of angiotensin II type I receptor antagonists. Pediatr Nephrol. 21(5):729-32.
  • Diav-Citrin O, et al. 2011. Pregnancy outcome after in utero exposure to angiotensin converting enzyme inhibitors or angiotensin receptor blockers. Reprod Toxicol. 31(4):540-545.
  • Gersak K, et al. 2009. Angiotensin II receptor blockers in pregnancy: a report of 5 cases. Reprod Toxicol. 28(1):109-12.
  • Lambot M, et al. 2001. Angiotensin-II-receptor inhibitors in pregnancy. Lancet. 357:1619-1620.
  • Marin EC, et al. 2014. The role of oxidative stress in renal injury induced in rats by losartan exposure during lactation. J Renin Angiotensin Aldosterone Syst. 15(4): 362-377.
  • Martinovic J, et al. 2001. Fetal toxic effects and angiotensin-II-receptor antagonists. Lancet. 358:241-242.
  • Saji H, et al. 2001. Losartan and fetal toxic effects. Lancet. 357:363.
  • Schaefer C. 2003. Angiotensin II-receptor-antagonists: further evidence of fetotoxicity but not teratogenicity. Birth Defects Res Part A Clin Mol Teratol. 67:591-594.
  • Serreau R, et al. 2005. Developmental toxicity of the angiotensin II type 1 receptor antagonists during human pregnancy: a report of 10 cases. BJOG. 112(6):710-712.
  • Sica DA, et al. 2005. Clinical pharmacokinetics of losartan. Clin Pharmacokinet. 44(8):797-814.
  • Spaggiari E, et al. 2012. Renin-Angiotensin System Blockers Study Group, Muller F. Prognosis and outcome of pregnancies exposed to renin-angiotensin system blockers. Prenat Diagn. 18:1-6.
  • Spence SG, et al. 1995. Evaluation of the reproductive and developmental toxicity of the AT1-selective angiotensin II receptor antagonist losartan in rats. Teratology. 51:383-97.
  • Stevenson KM, et al. 1996. Effects of losartan on the cardiovascular system, renal haemodynamics and function and lung liquid flow in fetal sheep. Clin Exp Pharmacol Physiol. 23:125-33.
  • Wei Q, et al. 2021. Use of angiotensin II receptor blocker during pregnancy: A case report. Medicine (Baltimore). 22;100(3):e24304.

Footer

           

Hot Links

  • Home
  • Exposures
  • Fact Sheets
  • Baby Blogs
  • Podcasts
  • Pregnancy Studies
  • Join a Study Now
  • Healthcare Professionals
  • Refer a Patient
  • Request Materials
  • News
  • Donate
  • Ask An Expert

Current Studies

  • Ankylosing Spondylitis
  • Asthma
  • Coronavirus (COVID-19)
  • Crohn’s Disease
  • Eczema (Moderate-to-Severe)/Atopic Dermatitis
  • Juvenile Idiopathic Arthritis
  • Multiple Sclerosis
  • Pertussis/Tdap vaccine (“Whooping Cough” vaccine)
  • Psoriasis
  • Psoriatic Arthritis
  • Rheumatoid Arthritis
  • Ulcerative Colitis

Contact

Exposure Information Service
866.626.6847

Pregnancy Studies
877.311.8972

Media Inquiries
619.368.3259
nchavez@mothertobaby.org

MotherToBaby, a service of the Organization of Teratology Information Specialists
OTIS Logo

Copyright © 2023 The Organization of Teratology Information Specialists

  • Accessibility
  • Privacy
  • Terms
  • Site Map
^