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Hydroxychloroquine

April 1, 2024

Selected References:

  • Andersson NK, et al. 2021. Fetal safety of chloroquine and hydroxychloroquine use during pregnancy: a nationwide cohort study. Rheumatol 14;60(5):2317-2326.
  • Bérard A, et al. 2021. Chloroquine and hydroxychloroquine use during pregnancy and the risk of adverse pregnancy outcomes using real-world evidence. Front Pharmacol 2;12:722511.
  • Bermas BL, et al. 2018. Trends in use of hydroxychloroquine during pregnancy in systemic lupus erythematosus patients from 2001 to 2015. Lupus 1:961203317749046.
  • Buchanan NMM, et al. 1996. Hydroxychloroquine and lupus pregnancy: review of a series of 36 cases. Ann Rheum Dis 55(7):486-488.
  • Centers for Disease Control and Prevention (CDC). 2022. Malaria Disponible en URL: https://www.cdc.gov/parasites/malaria/index.html.
  • Centers for Disease Control and Prevention (CDC). 2020. Treatment of Malaria: Guidelines for Clinicians (United States): Alternatives for Pregnant Women. Disponible en URL: https://www.cdc.gov/malaria/diagnosis_treatment/clinicians1.html#pregnant.
  • Chambers CD, et al. 2022. Birth outcomes in women who have taken hydroxychloroquine during pregnancy: a prospective cohort study. Arthritis Rheumatol 74(4):711-724.
  • Cimaz R, et al. 2004. Electroretinograms of children born to mothers treated with hydroxychloroquine during pregnancy and breast-feeding: comment on the article by Costedoat-Chalumeau et al. Arthritis Rheum 50(9):3056-3057.
  • Clowse ME, et al. 2006. Hydroxychloroquine in lupus pregnancy. Arthritis Rheum 54(11):3640-3647.
  • Costedoat-Chalumeau N, et al. 2003. Safety of hydroxychloroquine in pregnant patients with connective tissue diseases: a study of one hundred thirty-three cases compared with a control group. Arthritis Rheum 48(11):3207-3211.
  • Diav-Citrin O, et al. 2013. Pregnancy outcome following in utero exposure to hydroxychloroquine: a prospective comparative observational study. Reprod Toxicol 39:58-62.
  • Feldkamp M & Carey JC 1993. Clinical teratology counseling and consultation case report: low dose methotrexate exposure in the early weeks of pregnancy. Teratology 47(6):533-539.
  • Flint J, et al. 2016. BSR and BHPR guideline on prescribing drugs in pregnancy and breastfeeding-Part I: standard and biologic disease modifying anti-rheumatic drugs and corticosteroids. Rheumatology (Oxford) [Internet];55(9):1693e7
  • Frassi M, et al. 2004. Hydroxychloroquine in pregnant patients with rheumatic disease: a case control observation of 76 treated pregnancies. Lupus 13(9):755.
  • Howley MM, et al. 2021. Maternal exposure to hydroxychloroquine and birth defects. Birth Defects Res 113(17):1245-1256.
  • Huybrechts KF, et al. 2021. Hydroxychloroquine early in pregnancy and risk of birth defects. Am J Obstet Gynecol 224(3):290.e1-290.e22.
  • Ingster-Moati I and Albuisson E. 2010. Visual neurophysiological dysfunction in infants exposed to hydroxychloroquine in utero. Acta Paediatr 99(1):4; author reply 4-5.
  • Kaplan YC, et al. 2016. Reproductive outcomes following hydroxychloroquine use for autoimmune diseases: a systematic review and meta-analysis. Br J Clin Pharmacol 81:835-848.
  • Kroese SJ, et al. 2017. Hydroxychloroquine use in lupus patients during pregnancy is associated with longer pregnancy duration in preterm births. J Immunol Res 2017:2810202.
  • Levy RA, et al. 2001. Hydroxychloroquine (HCQ) in lupus pregnancy: double-blind and placebo-controlled study. Lupus10: 401–4.
  • Mirzaei M, et al. 2023.The effects of hydroxychloroquine on pregnancy outcomes in infertile women: a systematic review and meta-analysis. J Med Life 16(2):189-194.
  • Mouyis M, et al. 2019. Safety of anti-rheumatic drugs in men trying to conceive: a systematic review and analysis of published evidence. Semin Arthritis Rheumat 48(5): 911-920.
  • National Institute of Health. 2021. Product label: hydroxychloroquine sulfate tablet. Disponible en URL: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=84b00366-96ef-41e1-bac6-5d24acdb9e1d.
  • Sammaritano LR, et al. 2020 American College of Rheumatology Guideline for the Management of Reproductive Health in Rheumatic and Musculoskeletal Diseases. Arthritis Rheumatol 72(4):529–56.
  • Silver R, et al. 2023. Society for Maternal-Fetal Medicine Consult Series #64: Systemic lupus erythematosus in pregnancy. Am J Obstet Gynecol 228(3):B41-B60.
  • Sperber K, et al. 2009. Systematic review of hydroxychloroquine use in pregnant patients with autoimmune diseases. Pediatr Rheumatol Online J 13:7:9.
  • Tian Y, et al. 2021. The additional use of hydroxychloroquine can improve the live birth rate in pregnant women with persistent positive antiphospholipid antibodies: A systematic review and meta-analysis. J Gynecol Obstet Hum Reprod 50:1-6.

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