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Medications and More during pregnancy and breastfeeding

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Low Dose Aspirin

Selected References:

  • Abdi N, et al. 2020. The effect of aspirin on preeclampsia, intrauterine growth restriction and preterm delivery among healthy pregnancies with a history of preeclampsia. J Chin Med Assoc 83(9):852-857.
  • 2014. Summaries for patients: aspirin to prevent preeclampsia-related complications and death: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med 161(11): I28.
  • Bermas B, et al. 2014. Effects of anti-inflammatory and immunosuppressive drugs on gonadal function in men with rheumatic diseases. Retrieved August 27, 2015 from http://www.uptodate.com
  • Bloor M, Paech M. 2013. Nonsteroidal anti-inflammatory drugs during pregnancy and the initiation of lactation. Anesth Analg 116(5):1063-75.
  • Datta P, et al. 2017. Transfer of low dose aspirin into human milk. J Hum Lact 33(2):296-299.
  • Ellfolk M, Hultzsch S. 2015. Analgesics, antiphlogistics and anesthetics. In C Schaefer, P Peters, R Miller (Eds.), Drugs During Pregnancy and Lactation: Treatment Options and Risk Assessment. 3rd ed. 653-655. London: Elsevier.
  • Grab D, et al. 2000. Effects of low-dose aspirin on uterine and fetal blood flow during pregnancy: results of a randomized, placebo-controlled, double-blind trial. Ultrasound Obstet Gynecol 15:19-27.
  • LeFevre ML, U.S. Preventive Services Task Force. 2014. Low-dose aspirin use for the prevention of morbidity and mortality from preeclampsia: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med 161(11):819-26.
  • Maher JE, et al. 1993. The effect of low-dose aspirin on fetal urine output and amniotic fluid volume. Am J Obstet Gynecol 169:885-8.
  • Malm H, Borish C. 2015. Analgesics, non-steroidal anti-inflammatory drugs (NSAIDS), muscle relaxants, and antigout medications. In C Schaefer, P Peters, R Miller (Eds.), Drugs During Pregnancy and Lactation: Treatment Options and Risk Assessment, 3rd ed. 27-32. London: Elsevier.
  • Marret, S. et. al. 2010. Prenatal Low-Dose Aspirin and Neurobehavioral Outcomes of Children Born Very Preterm. Pediatrics 125(1):e29-e34.
  • Martini A, et al. 2003. Analysis of semen from patients chronically treated with low or moderate doses of aspirin-like drugs. Fertil and Steril 80(1):221-222.
  • Mone F, McAuliffe FM. 2015. Preconception low-dose aspirin and pregnancy outcomes: results from the EAGeR randomized trial. Ir Med J. Jan;08(1):5.
  • Naimi A, et al. 2021. The Effect of Preconception-Initiated Low-Dose Aspirin on Human Chorionic Gonadotropin Detected Pregnancy, Pregnancy Loss, and Live Birth. Annals of Internal Medicine May;174(5):595-601.
  • Ostensen M, et al. 2006. Anti-inflammatory and immunosuppressive drugs and reproduction. Arthritis Res Ther 8(3):1-19.
  • Schisterman EF, et al. 2015. Preconception low dose aspirin and time to pregnancy: findings from the effects of aspirin in gestation and reproduction randomized trial. J Clin Endocrinol Metab May; 100(5):1785-91.
  • Spigset O, et al. 2000. Analgesics and breast-feeding: safety considerations. Paediatr Drugs 2(3):223-38.