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MotherToBaby

Medications and More during pregnancy and breastfeeding

Ofloxacin

Selected References:

  • Aagaard J, et al. 1991. Prostatic tissue levels of ofloxacin. Urology, 38:380-382.
  • Cahill JB Jr, et al. 2005. Levofloxacin secretion in breast milk: a case report. Pharmacotherapy, 25:116-118.
  • Caplin Sterile Limited. 2024. Ofloxacin product label. Available at: https://dailymed.nlm.nih.gov/dailymed/drugInfo. Accessed June 20 2024.
  • Danisovicova A, et al. 1994. Magnetic resonance imaging in children receiving quinolones: no evidence of quinolone-induced arthropathy. A multicenter survey. Chemotherapy, 40:209-214.
  • Drobac PC, et al. 2005. Treatment of multidrug-resistant tuberculosis during pregnancy: long-term follow-up of 6 children with intrauterine exposure to second-line agents. Clin Infect Dis, 40:1689-1692.
  • Erhart B, et al. 1998. Ofloxacin: the next generation of antibiotic in sperm and embryo cultures for assisted reproductive technologies. Fertil Steril, 69(2):246-251.
  • Falagas ME, et al. 2007. Arrhythmias associated with fluoroquinolone therapy. Int J Antimicrob Agents, 29(4):374-379.
  • Giamarellou H, et al. 1989. Pharmacokinetics of three newer quinolones in pregnant and lactating women. Am J Med, 87(5A):49S-51S.
  • Loebstein R, et al. 1998. Pregnancy outcome following gestational exposure to fluoroquinolones: a multicenter prospective controlled study. Antimicrob Agents Chemother, 42:1336-1339.
  • Muanda Ft, et al. 2017. Use of antibiotics during pregnancy and the risk of major congenital malformations: a population based cohort study. Br J Clin Pharmacol, 83:2557-2571.
  • Naber KG, et al. 1993. Penetration of ofloxacin into prostatic fluid, ejaculate and seminal fluid. Infection, 21(2):98-100.
  • Nivagen Pharmaceuticals Inc. 2023. Ofloxacin product label. Available at: https://dailymed.nlm.nih.gov/dailymed/drugInfo. Accessed June 20 2024.
  • Padberg S, et al. 2014. Observational cohort study of pregnancy outcomes after first-trimester exposure to fluoroquinolones. Antimicrob Agents Chemother, 58(8):4392-4398.
  • Peled Y, et al. 1991. Ofloxacin during the second trimester of pregnancy. DICP, 25(11):1181-1182.
  • Schaefer C, et al. 1996. Pregnancy outcome after prenatal quinolone exposure. Evaluation of a case registry of the European Network of Teratology Information Services (ENTIS). Eur J Obstet Gynecol Reprod Biol, 69(2):83-89.
  • Schramm P. 1986. Ofloxacin: concentration in human ejaculate and influence on sperm motility. Infection, 14 Suppl 4:S274-S275.
  • Shao S, et al. 2023. Association between antibiotic exposure and the risk of infertility in women of childbearing age: a case-control study. Ecotoxicol Environ Saf, 249: 114414.
  • Shin YJ, et al. 2018. Pregnancy outcomes in women reporting exposure to ofloxacin in early pregnancy. J Obstet Gynaecol, 38(6):807-812.
  • Wilton LV, et al. 1998. The outcomes of pregnancy in women exposed to newly marketed drugs in general practice in England. British J Obstet Gynecol, 105:882-889.
  • Yamaguchi H, et al. 2007. Post-marketing surveillance of the safety of levofloxacin in Japan. Chemotherapy, 53(2):85-103.

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