MotherToBaby

Medications and More during pregnancy and breastfeeding

Search

866.626.6847

Ciprofloxacin (Cipro®)

Selected References:

  • AAP Committee on Drugs. 2001. The transfer of drugs and other chemicals into human milk. Pediatrics 108:776-789.
  • Acar S, et al. 2019. Pregnancy outcomes following quinolone and fluoroquinolone exposure during pregnancy: A systematic review and meta-analysis. Reprod Toxicol, 85:65-74.
  • Berkovitch M, et al. 1994. Safety of the new quinolones in pregnancy. Obstet Gynecol, 84(4):535-538.
  • Bomford JAL, et al. 1993. Ciprofloxacin use during pregnancy. Drugs, 45(S3): 461-462.
  • Cavusoglu I, et al. 2016. Evaluation of teratogenic effects of ciprofloxacin in pregnant women exposed due to urinary tract infections (abstract). Reprod Toxicol, 60:178.
  • Cover DL, Mueller BA. 1990. Ciprofloxacin penetration into human breast milk: a case report. DICP, 24:703-704.
  • Gardner D, et al. 1992. Simultaneous concentrations of ciprofloxacin in breast milk and in serum in mother and breast-fed infant. Clin Pharm, 11:352-354.
  • Kabeya CM, et al. 1995. Ciprofloxacin for multiresistant enteric fever in pregnancy. The Lancet, 346:307-308.
  • Leung D, et al. 1995. Treatment of typhoid in pregnancy. The Lancet, 346:648.
  • Loebstein R, et al. 1998. Pregnancy outcome following gestational exposure to fluoroquinolones: a multicenter prospective controlled study. Antimicrob Agents Chemother, 42(6):1336-1339.
  • Meaney-Delman D, et al. 2013 Prophylaxis and treatment of anthrax in pregnant women. Obstet Gynecol, 122(4):885-900.
  • Nahum G, et al. 2006. Antibiotic use in pregnancy and lactation. Obstet Gynecol, 107(5):1120-1138.
  • Noergaard M, et al. 2022. Ciprofloxacin exposure and adverse pregnancy outcomes: A Danish nationwide cohort study. BJOG, 129(9):1503-1511.
  • Padberg S, et al. 2014. Observational cohort study of pregnancy outcomes after first-trimester exposure to fluoroquinolones. Antimicrob Agents Chemother, 58(8):4392-4398.
  • Schaefer C, et al. 1996. Pregnancy outcome after prenatal quinolone exposure: evaluation of a case registry of the European Network of Teratology Information Services (ENTIS). Eur J Obstet Gynecol, 69:83-89.
  • Schluter G. 1989. Ciprofloxacin: toxicologic evaluation of additional safety data. The Am J Med, 87(5A):S37-S39.
  • Van Wattum JJ, et al. 2019. Antibiotics and lactation: An overview of relative infant doses and a systematic assessment of clinical studies. Basic Clin Pharmacol Toxicol, 124(1):5-17.
  • Yefet E, et al. 2018. The safety of quinolones and fluoroquinolones in pregnancy: a meta-analysis. doi: 10.1111/1471-0528.15119.

This website is supported by the Health Resources and Services Administration (HRSA) of the U.S. Department of Health and Human Services (HHS) as part of an award totaling $6,000,000 with zero percentage financed with non-governmental sources. The contents are those of the author(s) and do not necessarily represent the official views of, nor an endorsement by, HRSA, HHS, or the U.S. Government.