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Docusate Sodium

January 1, 2025

Selected References:

  • Aselton P, et al. 1984. First-trimester drug use and congenital disorders. Obstet Gynecol,65(4):451- 455.
  • Brigstocke S, et.al 2022. Review of the Safety Profiles of Laxatives in Pregnant Women. J Clin Gastroenterol, 56(3):197-203.
  • Greenhalf JO, Leonard HS. 1973. Laxatives in the treatment of constipation in pregnant and breast-feeding mothers. Practitioner; 210:259-63.
  • Hale, TW. 2012. Medications and Mothers’ Milk. Fifteenth Edition. Amarillo, TX: Hale Publishing L.P.
  • Heinonen OP, et al. 1977. Birth Defects and Drugs in Pregnancy. Littleton, Mass.: John Wright-PSG, pp 385, 442.
  • Jick H, et al. 1981. First-trimester drug use and congenital disorders. JAMA,246(4):343-346.
  • Laden S. 2019. OTC Medication Use in Pregnancy and Breastfeeding. US Pharmacist, 44(9):16-19
  • Lameris AL, et al. 1979. Drug induced alterations in Mg2+ homeostasis. Clinical Science,123(1):1.
  • MacKenzie K, et al. 1990. Three-generation reproduction study with dioctyl sodium sulfosuccinate in rats. Fundam Appl Toxicol,15:53-62.
  • Mahadevan U, & Kane S. 2006. American Gastroenterological Association Institute technical review on the use of gastrointestinal medications in pregnancy. Gastroenterology,131(1):283-311.
  • Rungsiprakarn P, et al. 2015. Interventions for treating constipation in pregnancy. Cochrane Database Syst Rev, Sep 4;2015(9):CD011448
  • Schindler AM. 1984. Isolated neonatal hypomagnesaemia associated with maternal overuse of stool softener. Lancet,2:822.
  • Thorpe PG, et al. 2013. Medications in the first trimester of pregnancy: most common exposures and critical gaps in understanding fetal risk. Pharmacoepidemiol Drug Safe, 22(9): 1013-1018.
  • Zielinski R, et al. 2015. Gastrointestinal distress in pregnancy: prevalence, assessment, and treatment of 5 common minor discomforts. J Perinat Neonatal Nurs, 29(1):23-31.

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