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Levonorgestrel (Plan B One-Step®)

Selected References:

  • Carvajal A, et al. 2015. Emergency contraceptive pill safety profile. Comparison of the results of a follow-up study to those coming from spontaneous reporting. Pharmacoepidemiology and Drug Safety 24(1): 93–97.
  • De Santis M, et al. 2005. Failure of the emergency contraceptive levonorgestrel and the risk of adverse effects in pregnancy and on fetal development: an observational cohort study. Fertility and Sterility 84(2):296–299.
  • Endler M, et al. 2022. Effect of levonorgestrel emergency contraception on implantation and fertility: A review. Contraception 109:8-18.
  • Gainer E, et al. 2007. Levonorgestrel pharmacokinetics in plasma and milk of lactating women who take 1.5 mg for emergency contraception. Hum Reprod 22(6):1578-84.
  • Leelakanok N. & Methaneethorn J. 2020. A systematic review and meta-analysis of the adverse effects of levonorgestrel emergency oral contraceptive. Clinical Drug Investigation 40(5):395–420.
  • Mierzejewska A, et al. 2024. Emergency contraception – a narrative review of literature. Eur J Obstet Gynecol Reprod Biol 299:188-192.
  • Polakow-Farkash S et al. 2013. Levonorgestrel used for emergency contraception during lactation-A prospective observational cohort study on maternal and infant safety. J Matern Fetal Neonatal Med 26:219-221.
  • Shohel M, et al. 2014. A systematic review of effectiveness and safety of different regimens of levonorgestrel oral tablets for emergency contraception. BMC Women’s Health 14(54).
  • Shurie S, et al. 2018. Levonorgestrel only emergency contraceptive use and risk of ectopic pregnancy in Eldoret Kenya: a case-control study. The Pan African Medical Journal 31(214).
  • Shaaban OM et al. 2019. Levonorgestrel emergency contraceptive pills use during breastfeeding; effect on infants’ health and development. J Matern Fetal Neonatal Med 32:2524–2528.
  • Trussell J, et al. 2003. Ectopic pregnancy following use of progestin-only ECPs. J Fam Plann Reprod Health Care 29(4):249.
  • von Hertzen H, et al. 2002. Low dose mifepristone and two regimens of levonorgestrel for emergency contraception: a WHO multicentre randomised trial. Lancet 360(9348):1803-1810.
  • Zhang J, et al. 2015. Association between levonorgestrel emergency contraception and the risk of ectopic pregnancy: a multicenter case-control study. Sci Rep 5(8487)

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