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Lidocaine

May 1, 2023

Selected References:

  • Abboud TK, et al. 1983. Lack of adverse neonatal neurobehavioral effects of lidocaine. Anesth Analg; 62:473-5.
  • Abboud TK, et al. 1984. Continuous infusion epidural analgesia in parturients receiving bupivacaine, chloroprocaine, or lidocaine – maternal, fetal, and neonatal effects. Anesth Analg; 63:421-8.
  • Actavis Pharma, Inc. 2019. Lidocaine and Prilocaine Cream Drug Label. Available at: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1972d657-2d5a-4697-bba9-80caffc2f2d7
  • Demeulemeester V, et al. 2018. Transplacental lidocaine intoxication. J Neonatal-Perinatal Med; 11:439-441.
  • Dryden RM, Lo MW. 2000. Breast milk lidocaine levels in tumescent liposuction. Plast Reconstr Surg; 105:2267-8.
  • Favero V, et al. 2021. Pregnancy and Dentistry: A Literature Review on Risk Management during Dental Surgical Procedures. Dent J (Basel). 9(4):46.
  • Fujinaga M, Mazze RI. 1986. Reproductive and teratogenic effects of lidocaine in Sprague-Dawley rats. Anesthesiology. 65:626-632.
  • Heinonen OP. et al. 1977. Birth Defects and Drugs in Pregnancy. Publishing Sci Group, Littleton, MA.
  • Kuhnert BR, et al. 1984. Effects of maternal epidural anesthesia on neonatal behavior. Anesth Analg; 63:301-8.
  • Kuhnert BR, et al. 1986. Lidocaine disposition in mother, fetus, and neonate after spinal anesthesia. Anesth Analg 65:139-44.
  • Lebedevs TH, et al. 1993. Excretion of lignocaine and its metabolite monoethylglycinexylidide in breast milk following its use in a dental procedure. A case report. J Clin Periodontol 20: 606-8.
  • Ortega D, et al. 1999. Excretion of lidocaine and bupivacaine in breast milk following epidural anesthesia for cesarean delivery. Acta Anaesthesiol Scand; 43:394-7.
  • Silveira MPT, et al. 2020. Breastfeeding and risk classification of medications used during hospitalization for delivery: 2015 Pelotas Birth Cohort. Rev Bras Epidemiol. 23:e200026.
  • Watson PD, Ott MA. 1982. Lidocaine and mepivacaine in cord blood. Ped Pharm; 2:341-348.
  • Zeisler JA, et al. 1986. Lidocaine excretion in breast milk. Drug Intell Clin Pharm; 20:691-3.

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