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Ziprasidone (Geodon®)

Selected References

  • Anghelescu I, et al. 2004. Successful switch to aripiprazole after induction of hyperprolactinemia by ziprasidone: a case report. J Clin Psychiatry 65:1286-1287.
  • Biesdorf C, et al. 2019. Physiologically-based pharmacokinetics of ziprasidone in pregnant women. Br J Clin Pharmacol 85(5):914-923.
  • Bode’n R, et al. 2012. Antipsychotics During Pregnancy Relation to Fetal and Maternal Metabolic Effects. Arch Gen Psychiatry 69(7):715-721.
  • Creeley CE, et al. 2019. Use of Prescribed Psychotropics during Pregnancy: A Systematic Review of Pregnancy, Neonatal, and Childhood Outcomes. Brain Sci. 9(9), 235. https://doi.org/10.3390/brainsci9090235
  • Damkier P, Videbech P. 2018. The safety of second-generation antipsychotics during pregnancy: A clinically focused review. CNS Drugs. 32(4):351-366.
  • Einarson A, Boskovic R. 2009. Use and safety of antipsychotic drugs during pregnancy. J Psychiatr Pract 15(3):183-192.
  • FDA. 2011. Drug Safety Communication: Antipsychotic drug labels updated on use during pregnancy and risk of abnormal muscle movements and withdrawal symptoms in newborns (issued 2/2011). https://www.fda.gov/Drugs/DrugSafety/ucm243903.htm
  • FDA 2014. Drug Safety Communication: FDA reporting mental health drug ziprasidone (Geodon) associated with rare but potentially fatal skin reactions. (Issued 12/2014). https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-fda-reporting-mental-health-drug-ziprasidone-geodon-associated-rare#:~:text=Ziprasidone%20is%20marketed%20under%20the%20brand%20name%20Geodon%2C%20and%20as%20generics.
  • Ginsberg DL. 2003. Ziprasidone-induced galactorrhea. Prim Psychiatry 10:22-23.
  • Ginsbery DL. 2004. Ziprasidone-induced hyperprolactinemia. Prim Psychiatry 11:26–27.
  • Goodnick PJ, et al. 2002. Antipsychotics: Impact on prolactin levels. Expert Opin Pharmacother 3:1381–1391.
  • Haddad PM, Wieck A. 2004. Antipsychotic-induced hyperprolactinaemia: mechanisms, clinical features and management. Drugs 64:2291-2314.
  • Heinonen E, et al. 2022. Antipsychotic Use During Pregnancy and Risk for Gestational Diabetes: A National Register-Based Cohort Study in Sweden. CNS drugs 36(5):529–539.
  • Humby T, Davies W. 2019. Brain gene expression in a novel mouse model of postpartum mood disorder. Trans Neurosci 10:168-174.
  • Huybrechts KF, et al. 2016. Antipsychotic use in pregnancy and the risk for congenital malformations. JAMA Psychiatr 73(9):938-46.
  • Huybrechts KF, et al. 2023. Association of In Utero Antipsychotic Medication Exposure With Risk of Congenital Malformations in Nordic Countries and the US. JAMA psychiatry 80(2):156–166.
  • Jordan MP. 2003. Ziprasidone-associated galactorrhea in a female teenager. J Am Acad Child Adolesc Psychiatry 42:4-5.
  • Khan SJ, et al. 2016. Bipolar disorder in pregnancy and postpartum: Principles of management. Curr Psychiatry Rep; 18(2):13.
  • Kopecek M, et al. 2005. Ziprasidone-induced galactorrhea: A case report. Neuro Endocrinol Lett 26:69–70.
  • Kulkarni J, et al. 2015. Antipsychotic use in pregnancy. Expert Opin Pharmacother 16(9):1335-1345.
  • Lusskin SI, et al. 2004. Prolactin Elevation with Ziprasidone. American Journal of Psychiatry 161(10): 1925.
  • Maguire GA. 2002. Prolactin elevation with antipsychotic Medications: Mechanisms of action and clinical consequences. J Clin Psychiatry 63 Suppl 4:56–62.
  • McCauley-Elsom K, et al. 2010. Antipsychotics in pregnancy. Psychiat Ment Health Nurs 17(2):97-104.
  • Myers WT. 2014. A lacting adolescent on atypical antipsychotics: A case report of an emerging challenge. J Investig Med 62:485.
  • Park Y, et al. 2018. Continuation of atypical antipsychotic medication during early pregnancy and the risk of gestational diabetes. Am J Psychiatry 175(6):564-574
  • Peitl MV, et al. 2010. Ziprasidone as a possible cause of cleft palate in a newborn. Psychiatr Danub 22(1):117-119.
  • Ramadan M, et al. 2005. D2-blockade and possible ziprasidone-induced galactorrhea. Int Clin Psychopharmacol 20:113–114.
  • Raza S, Haq F. 2010. Ziprasidone-induced galactorrhea in an adolescent female: A case report. Prim Care Companion J Clin Psych 12.
  • Ruzic K, et al. 2009. Pregnancy and atypical antipsychotics. Psychiatr Danub 21(3):368-370.
  • Saldaña SN, Delgado SV. 2007. Ziprasidone-associated galactorrhea in an adolescent female. J Child Adolesc Psychopharmacol 17:259–260.
  • Schlotterbeck P, et al. 2009. Low concentration of ziprasidone in human milk: a case report. Int J Neuropsychopharmacology. 12(3) 437–438. https://doi.org/10.1017/S1461145709009936
  • Sørensen MJ, et al. 2015. Risk of fetal death after treatment with antipsychotic medications during pregnancy. PLoS One 10(7):e0132280.
  • Werremeyer A. 2009. Ziprasidone and citalopram use in pregnancy and lactation in a woman with psychotic depression. Am J Psychiatry 166(11):1298.
  • Uguz F. 2016. Second-generation antipsychotics during the lactation period: A comparative systematic review on infant safety. J Clin Psychopharmacol 36:244-252.
  • Uguz FJ. 2019. Antipsychotic use during pregnancy and the risk of gestational diabetes mellitus: A systematic review. Clin Psychopharmacol 39(2):162-167.

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