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Dextromethorphan

2026年7月1日

Selected References:

  • Aselton P, et al. 1985. First-trimester drug use and congenital disorders. Obstet Gynecol; 65(4):451-455. 
  • Cao Y, et al. 2021. Maternal use of cough medications during early pregnancy and selected birth defects: a US multisite, case–control study. BMJ Open; 11:e053604. 
  • Einarson A, et al. 2001. The safety of dextromethorphan in pregnancy: Results of a controlled study. Chest; 119(2):466-469. 
  • Heinonen OP, et al. 1977. Birth Defects and Drugs in Pregnancy. Littleton, Mass.: John Wright-PSG, page 382. 
  • Martinez-Frias ML, et al. 2001. Epidemiologic analysis of prenatal exposure to cough medicines containing dextromethorphan: no evidence of human teratogenicity. Teratology; 63(1):38-41. 
  • Shum S, et al. 2022. Infant dextromethorphan and dextrorphan exposure via breast milk from mothers who are CYP2D6 extensive metabolizers. J Clin Pharmacol; 62(6):747-755. 
  • Ward KE. 2005. Can Robitussin DM be used to treat cough during pregnancy? Med Health R I; 88(3):99-100. 

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