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Search Results for: leflunomide


Selected References: Arava Prescribing Information. Available online at [accessed Dec 2015]. Bérard A, et al. 2018. Leflunomide use during pregnancy and the risk of adverse pregnancy outcomes. Ann Rheum Dis Apr;77(4):500-509. Brent RL. 2001. Teratogen update: Reproductive risks of leflunomide (Arava); A pyrimidine synthesis inhibitor: Counseling women taking leflunomide before or during pregnancy and […]

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Leflunomide (Arava®)

This sheet talks about the risks that exposure to leflunomide can have during pregnancy. With each pregnancy, all women have a 3% to 5% chance of having a baby with a birth defect. This information should not take the place of medical care and advice from your health care provider. What is leflunomide? Leflunomide is […]

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Arava® (leflunomide)

Help Us Better Understand the Effects of Arava® (leflunomide) in Pregnancy Many women need to take medication during pregnancy to appropriately manage their chronic health condition. In some cases, avoiding or stopping medication use during pregnancy may be more harmful than taking medication. Yet fewer than 10% of medications have enough information to determine their […]

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Teriflunomide (Aubagio®)

This sheet talks about teriflunomide in a pregnancy or while breastfeeding. This information should not take the place of medical care and advice from your health care provider. What is teriflunomide? Teriflunomide is a prescription medication used to treat multiple sclerosis. It is a pill taken by mouth, typically once per day. It is marketed […]

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Selected References: • Amato MP and Portaccio E. 2015. Fertility, Pregnancy and Childbirth in Patients with Multiple Sclerosis: Impact of Disease-Modifying Drugs. CNS Drugs 29:207-220. • Andersen JB, et al. 2018. Pregnancy outcomes in men and women treated with teriflunomide. A population-based nationwide Danish registry study. Frontiers in Immunology 9(2706):1-7. • Cree BA. 2013. Update […]

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Rheumatoid Arthritis

Selected References: Brouwer J, et al. 2015. Brief Report: Miscarriages in Female Rheumatoid Arthritis Patients: Associations With Serologic Findings, Disease Activity, and Antirheumatic Drug Treatment. Arthritis Rheumatol. 67(7):1738-43. Brouwer J, et al. 2015. Fertility in women with rheumatoid arthritis: influence of disease activity and medication. Ann Rheum Dis. 74(10):1836-41. de Man YA, et al. 2014. […]

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Past Studies

Past Studies MotherToBaby research findings contribute significantly to the field of teratogenesis, which is the study of how birth defects develop. Our investigators present their research results yearly at numerous national scientific meetings and have a number of scientific publications in top peer reviewed journals. View our completed studies and publications below. Publications From Our […]

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  • "I really felt much more at ease after hearing MotherToBaby's insight and getting more knowledge on the usage of the medication I may take during pregnancy." - Blake from Illinois
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Meet An Expert

  • Dr. Adam is a pediatrician and medical geneticist, and is one of the specialists who evaluates the babies participating in MotherToBaby Pregnancy Studies. She is currently Professor in the Division of Genetic Medicine, Department of Pediatrics at the University of Washington. Her clinical responsibilities include pediatric care at Seattle Children’s Hospital, as well as counseling pregnant women through the Prenatal Diagnosis Center at the University of Washington.

    - Margaret Adam, MD
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Help us help women and their healthcare providers as they make treatment choices in pregnancy and while breastfeeding.


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