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Search Results for: leflunomide


Selected References: Arava Prescribing Information. Available online at [accessed Dec 2015]. Bérard A, et al. 2018. Leflunomide use during pregnancy and the risk of adverse pregnancy outcomes. Ann Rheum Dis Apr;77(4):500-509. Brent RL. 2001. Teratogen update: Reproductive risks of leflunomide (Arava); A pyrimidine synthesis inhibitor: Counseling women taking leflunomide before or during pregnancy and […]

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Leflunomide (Arava®)

This sheet talks about the risks that exposure to leflunomide can have during pregnancy. With each pregnancy, all women have a 3% to 5% chance of having a baby with a birth defect. This information should not take the place of medical care and advice from your health care provider. What is leflunomide? Leflunomide is […]

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Arava® (leflunomide)

Help Us Better Understand the Effects of Arava® (leflunomide) in Pregnancy Many women need to take medication during pregnancy to appropriately manage their chronic health condition. In some cases, avoiding or stopping medication use during pregnancy may be more harmful than taking medication. Yet fewer than 10% of medications have enough information to determine their […]

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Planning a Healthy Pregnancy

By Beth Kiernan, MPH Tanya called in on a Monday morning. “I’m getting married in a few months and we want to start trying to get pregnant right away. What should I be doing now to have the best chance of a healthy baby?” Preconception health and pregnancy planning present a terrific opportunity to assess […]

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Teriflunomide (Aubagio®)

This sheet talks about teriflunomide in a pregnancy or while breastfeeding. This information should not take the place of medical care and advice from your health care provider. What is teriflunomide? Teriflunomide is a prescription medication used to treat multiple sclerosis. It is a pill taken by mouth, typically once per day. It is marketed […]

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Selected References: • Amato MP and Portaccio E. 2015. Fertility, Pregnancy and Childbirth in Patients with Multiple Sclerosis: Impact of Disease-Modifying Drugs. CNS Drugs 29:207-220. • Andersen JB, et al. 2018. Pregnancy outcomes in men and women treated with teriflunomide. A population-based nationwide Danish registry study. Frontiers in Immunology 9(2706):1-7. • Cree BA. 2013. Update […]

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Rheumatoid Arthritis

Selected References: Brouwer J, et al. 2015. Brief Report: Miscarriages in Female Rheumatoid Arthritis Patients: Associations With Serologic Findings, Disease Activity, and Antirheumatic Drug Treatment. Arthritis Rheumatol. 67(7):1738-43. Brouwer J, et al. 2015. Fertility in women with rheumatoid arthritis: influence of disease activity and medication. Ann Rheum Dis. 74(10):1836-41. de Man YA, et al. 2014. […]

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Past Studies

Past Studies MotherToBaby research findings contribute significantly to the field of teratogenesis, which is the study of how birth defects develop. Our investigators present their research results yearly at numerous national scientific meetings and have a number of scientific publications in top peer reviewed journals. View our completed studies and publications below. Publications From Our […]

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  • "I cannot tell you how much I appreciate the level of detail you provided. I now feel I can make a more informed decision as I move forward with treatment." - Julie from Illinois
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Meet An Expert

  • Patricia Cole is the Program Coordinator for MothertoBaby Massachusetts. She obtained her Bachelor’s degree in Biology from Simmons College in Boston and her MPH in Maternal and Child Health from Boston University School of Public Health. She has been the serving the families of New England as a teratogen counselor since 2001 and provides oversight for the day-to-day functions and outreach of the program. She has also provides education to graduate students and other professionals.

    - Patricia Cole, MPH
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