Selected References: Ahn HK, et al. 2007. Exposure to amlodipine in the first trimester of pregnancy and during breastfeeding. Hypertension in pregnancy, 26(2):179–187. Aoki H, et al. 2018. Low Levels of Amlodipine in Breast Milk and Plasma. Breastfeeding medicine,13(9):622–626. Centers for Disease Control and Prevention. (2024). Health and economic benefits of high blood pressure interventions. Retrieved August 2024 from …
The Baby Blog
About Our Baby Blog
Every person wants to know what’s best for their baby, especially when it comes to knowing how to minimize exposure risks. Our relatable stories are packed with practical information from our rotating staff of MotherToBaby expert bloggers. Whatever topic you’re looking for, our blogs will provide you a great foundation to learn more.
Mifepristone
Selected References: Auffret M, et al. 2016. Misoprostol exposure during the first trimester of pregnancy: Is the malformation risk varying depending on the indication? Eur J Obstet Gynecol Reprod Biol, 207:188-192. Baev OR, et al. 2017. Outcomes of mifepristone usage for cervical ripening and induction of labour in full-term pregnancy. Randomized controlled trial. Eur J Obstet Gynecol Reprod Biol, 217:144-149. Brown A, et al. 2002. Daily low dose mifepristone has contraceptive …
Nifedipine (Procardia®)
Selected References: American College of Obstetricians and Gynecologists (ACOG). 2022/Apr. Preeclampsia and High Blood Pressure during Pregnancy. https://www.acog.org/womens-health/faqs/preeclampsia-and-high-blood-pressure-during-pregnancy Anderson PO, et al 2020. Drug treatment of Raynaud’s phenomenon of the nipple. Breastfeed Med 15:686-8. Benoff S, et al. 1994. The effect of calcium ion channel blockers on sperm fertilization potential. Fertil Steril 62:606-17. Bortolus R, et …
Methimazole
Agrawal M, et al. 2022. Antithyroid drug therapy in pregnancy and risk of congenital anomalies: Systematic review and meta-analysis. Clinical endocrinology, 96(6):857–868. Akmal A, Kung J. 2014. Propylthiouracil, and methimazole, and carbimazole-related hepatotoxicity. Expert Opin Drug Saf, 13(10):1397-1406. Alexander EK, et al. 2017. 2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum. Thyroid: …
Topical Tretinoin
Selected References: Camera G and Pregliasco P. 1992. Ear malformation in baby born to mother using isotretinoin cream. Lancet, 339:687. De Wals P. et al. 1991. Association between holoprosencephaly and exposure to topical retinoids: results of the EUROCAT survey. Paediatr Perinat Epidemiol, 5:445-447. Jick S, et al. 1993. First trimester topical tretinoin and congenital disorders. Lancet, 341:1181-1182. Kaplan YC, et al. 2015. Pregnancy outcomes following first-trimester exposure …
